Invention Grant
- Patent Title: Filipil compositions and methods for treating cancer
- Patent Title (中): 菲利皮组合物和治疗癌症的方法
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Application No.: US12745279Application Date: 2008-12-08
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Publication No.: US08501912B2Publication Date: 2013-08-06
- Inventor: Steven K. Libutti , Mjung Kwon , Anita Tandle
- Applicant: Steven K. Libutti , Mjung Kwon , Anita Tandle
- Applicant Address: US DC Washington
- Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Woodcock Washburn LLP
- International Application: PCT/IB2008/005015 WO 20081208
- International Announcement: WO2010/070380 WO 20100624
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61P35/00 ; C07K14/00
Abstract:
A purified DOC1 polypeptide comprising a fragment of SEQ ID NO: 1 is provided, wherein the DOC1 polypeptide is not the full-length DOC1 polypeptide sequence. A method of inhibiting angiogenesis in a subject is provided comprising administering to a subject a nucleic acid encoding a DOC1 polypeptide, whereby a cell in the subject produces the DOC1 polypeptide, thus inhibiting angiogenesis. A method of inhibiting tumor growth in a subject is provided comprising administering to a subject a nucleic acid encoding a DOC1 polypeptide, whereby a cell in the subject produces the DOC1 polypeptide, thus inhibiting tumor growth.
Public/Granted literature
- US20110053850A1 DOC1 COMPOSITIONS AND METHODS FOR TREATING CANCER Public/Granted day:2011-03-03
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