Invention Grant
US08501920B2 Nucleic acid sequences encoding peptides with utrophin spectrin-like repeats
有权
编码具有utrophin spectrin样重复肽的核酸序列
- Patent Title: Nucleic acid sequences encoding peptides with utrophin spectrin-like repeats
- Patent Title (中): 编码具有utrophin spectrin样重复肽的核酸序列
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Application No.: US11824870Application Date: 2007-07-03
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Publication No.: US08501920B2Publication Date: 2013-08-06
- Inventor: Jeffrey S. Chamberlain , Scott Q. Harper
- Applicant: Jeffrey S. Chamberlain , Scott Q. Harper
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of The University of Michigan
- Current Assignee: The Regents of The University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones, S.C.
- Main IPC: C07H21/02
- IPC: C07H21/02 ; A61K48/00
Abstract:
The present invention relates to compositions and methods for expressing mini-dystrophin peptides. In particular, the present invention provides compositions comprising nucleic acid sequences that are shorter than wild-type dystrophin cDNA and that express mini-dystrophin peptides that function in a similar manner as wild-type dystrophin proteins. The present invention also provides compositions comprising mini-dystrophin peptides, and methods for expressing mini-dystrophin peptides in target cells.
Public/Granted literature
- US20080167260A1 Nucleic acid sequences encoding peptides with utrophin spectrin-like repeats Public/Granted day:2008-07-10
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