Invention Grant
- Patent Title: Process for producing oseltamivir phosphate and intermediate compound
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Application No.: US12995059Application Date: 2009-05-28
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Publication No.: US08501980B2Publication Date: 2013-08-06
- Inventor: Yujiro Hayashi , Hayato Ishikawa
- Applicant: Yujiro Hayashi , Hayato Ishikawa
- Applicant Address: JP Tokyo
- Assignee: Sumitomo Chemical Company, Ltd.
- Current Assignee: Sumitomo Chemical Company, Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Dilworth & Barrese, LLP.
- Priority: JP2008-143226 20080530; JP2008-311543 20081205
- International Application: PCT/JP2009/059789 WO 20090528
- International Announcement: WO2009/145263 WO 20091203
- Main IPC: C07C323/30
- IPC: C07C323/30 ; C07C323/17

Abstract:
Disclosed are a process suited to large scale synthesis with high yield for producing oseltamivir phosphate, in which a preparation of oseltamivir phosphate which is highly safe as a pharmaceutical product can be produced, and an intermediate compound for producing oseltamivir phosphate. In this production process, an intermediate compound represented by general formula (V) is synthesized by employing Michael reaction/Michael reaction/Horner-Wadsworth-Emmons reaction, and oseltamivir phosphate is produced by converting the substituent groups in this intermediate compound.
Public/Granted literature
- US20110082302A1 Process for Producing Oseltamivir Phosphate and Intermediate Compound Public/Granted day:2011-04-07
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