An electrophoretic display structure includes a substrate, an activation layer, an electrophoretic display layer, a protective layer, a first sealant, and a second sealant. The activation layer is disposed on the substrate while the electrophoretic display layer is disposed on the activation layer. The electrophoretic display layer has a plurality of electrophoretic display elements and a waterproof layer disposed on the electrophoretic display elements. The protective layer is disposed on the electrophoretic display elements. The protective layer is disposed on the waterproof layer, and the first sealant is disposed between the activation layer and the protective layer to fill in the sides of the electrophoretic display layer. The second sealant covers the outer side of the first sealant and connects with the activation layer and the protective layer. The viscosity of the first sealant in liquid state is lower than the viscosity of the second sealant in liquid state.