Power supplies, power adapters, and related methods are disclosed. One example power supply includes an open loop DC to DC converter having an input for connecting to an input power source and an output for supplying a DC output voltage or current and an enable/disable circuit coupled to the open loop DC to DC converter. The enable/disable circuit is configured to enable and disable the open loop DC to DC converter as a function of the DC output voltage or current. One example method includes determining a DC output voltage or current from an open loop DC to DC converter and enabling and disabling the open loop DC to DC converter as a function of the determined DC output voltage or current.