Systems and methods to dynamically provision subscribers in a network are disclosed herein. An example method to provision a subscriber in a communication network includes detecting that a location of a subscriber has changed from a first region to a second region, determining that the communication network would benefit from permanently provisioning a customer profile associated with the subscriber to the second region instead of keeping the customer profile provisioned in the first region, instructing a first customer profile repository to transfer the customer profile to a second customer profile repository corresponding to the second region in response to detecting the location change and that the communication network would benefit, and provisioning the customer profile at the second customer profile repository.