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US08504160B2 System and method for modulating action potential propagation during spinal cord stimulation 有权
用于调节脊髓刺激期间动作电位传播的系统和方法

System and method for modulating action potential propagation during spinal cord stimulation
Abstract:
A method and neurostimulator for providing therapy to a patient is provided. In one technique, an electrical pulsed waveform is conveyed between a caudal electrode and spinal cord tissue, thereby evoking action potentials that are orthodromically propagated along dorsal column fibers and evoking action potentials that are antidromically propagated along the DC fibers. Electrical energy is conveyed between a rostral electrode and the spinal cord tissue, thereby modulating times that the action potentials orthodromically propagated along the DC fibers arrive at the brain. In another technique, an electrical pulsed waveform is conveyed through a first electrode, thereby evoking action potentials that are propagated along a neural axon, and electrical energy is conveyed through the second electrode. The electrical energy has a frequency that is greater than a pulse rate of the electrical pulsed waveform, such that the action potentials propagated along the neural axon are blocked by the electrical energy.
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