In certain embodiments of the present disclosure, a folding knife has a biasing mechanism, such as a spring, that applies an opening force to the blade when the blade is in the closed, or folded, position (i.e., the force of the spring creates a moment in the opening direction of the blade). The folding knife includes a latching mechanism that holds the blade in a closed and latched position against the opening force of the spring. To open the blade, manual pressure is applied to the upper edge of the blade (the edge opposite the sharpened edge) to move the blade slightly to a closed and unlatched position to release the blade from being held from the latching mechanism whereupon the blade is then free to pivot under the opening force of the spring.