Invention Grant
- Patent Title: Compositions comprising quinazoline derivatives
- Patent Title (中): 包含喹唑啉衍生物的组合物
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Application No.: US12993629Application Date: 2009-05-21
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Publication No.: US08507010B2Publication Date: 2013-08-13
- Inventor: Jianhui Guo , Haiying He
- Applicant: Jianhui Guo , Haiying He
- Applicant Address: CN
- Assignee: Shanghai Allist Pharmaceuticals, Inc.
- Current Assignee: Shanghai Allist Pharmaceuticals, Inc.
- Current Assignee Address: CN
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- Priority: CN200810043382 20080521
- International Application: PCT/CN2009/000557 WO 20090521
- International Announcement: WO2009/140863 WO 20091126
- Main IPC: A61K31/517
- IPC: A61K31/517 ; A61K33/24 ; A61P35/00 ; A61P27/02 ; A61P9/10 ; A61P29/00 ; A61P17/06 ; A61P11/00
Abstract:
The present invention provides a pharmaceutical composition, useful for the treatment of diseases characterized by abnormal PTKs activity of erbB family in a mammal, comprising pharmaceutically acceptable salts of N-{4-[3-chloro-4-(3-fluoro-benzyloxy) phenylamino]quinazolin-6-yl}-acrylamide, optionally a pharmaceutically applicable carrier or diluent, and a stabilizer having a dispersing and/or protective effect on the active ingredient. The present invention further provides a pharmaceutical formulation comprising said composition, methods for preparation of said composition and said formulation, as well as use of said composition and said formulation for treating diseases characterized by abnormal PTKs activity of erbB family in a mammal.
Public/Granted literature
- US20110111059A1 Compositions Comprising Quinazoline Derivatives, Preparation Methods and Uses Thereof Public/Granted day:2011-05-12
Information query
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