Invention Grant
US08507510B2 Sulfoximine-substituted pyrimidines as CDK- and/or VEGF inhibitors, their production and use as pharmaceutical agents
失效
磺酰亚胺取代的嘧啶作为CDK和/或VEGF抑制剂，其生产和用作药剂
- Patent Title: Sulfoximine-substituted pyrimidines as CDK- and/or VEGF inhibitors, their production and use as pharmaceutical agents
- Patent Title (中): 磺酰亚胺取代的嘧啶作为CDK和/或VEGF抑制剂，其生产和用作药剂
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Application No.: US12095947Application Date: 2004-10-12
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Publication No.: US08507510B2Publication Date: 2013-08-13
- Inventor: Ulrich Lücking , Martin Krüger , Rolf Jautelat , Gerhard Siemeister
- Applicant: Ulrich Lücking , Martin Krüger , Rolf Jautelat , Gerhard Siemeister
- Applicant Address: DE Monheim
- Assignee: Bayer Intellectual Property GmbH
- Current Assignee: Bayer Intellectual Property GmbH
- Current Assignee Address: DE Monheim
- Priority: DE10349423 20031016
- International Application: PCT/EP2004/011661 WO 20041012
- International Announcement: WO2005/037800 WO 20050428
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505 ; C07D239/02
Abstract:
This invention relates to pyrimidine derivatives of general formula I in which Q, R1, R2, R3, R4, R5, X, and m have the meanings that are contained in the description, as inhibitors of cyclin-dependent kinases and VEGF-receptor tyrosine kinases, their production as well as their use as medications for treatment of various diseases.
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