Invention Grant
- Patent Title: Selective heterocyclic sphingosine 1 phosphate receptor modulators
- Patent Title (中): 选择性杂环鞘氨醇1磷酸受体调节剂
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Application No.: US12946828Application Date: 2010-11-15
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Publication No.: US08507538B2Publication Date: 2013-08-13
- Inventor: Marcus F. Boehm , Esther Martinborough , Enugurthi Brahmachary , Manisha Moorjani , Junko Tamiya , Liming Huang , Adam Richard Yeager
- Applicant: Marcus F. Boehm , Esther Martinborough , Enugurthi Brahmachary , Manisha Moorjani , Junko Tamiya , Liming Huang , Adam Richard Yeager
- Applicant Address: US CA San Diego
- Assignee: Receptos, Inc.
- Current Assignee: Receptos, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Seed IP Law Group PLLC
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/496 ; A61K31/454 ; A61K31/433 ; A61K31/427 ; A61K31/426 ; A61K31/425 ; A61K31/381 ; C07D417/12 ; C07D417/10 ; C07D333/24 ; C07D333/22 ; C07D333/20 ; C07D333/16 ; C07D277/30 ; C07D277/28 ; C07D277/24 ; C07D285/12 ; C07D285/10 ; C07D285/08
Abstract:
Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds is provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.
Public/Granted literature
- US20110183953A1 SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS Public/Granted day:2011-07-28
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