Invention Grant
- Patent Title: Potassium channel blockers and uses thereof
- Patent Title (中): 钾通道阻滞剂及其用途
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Application No.: US12997864Application Date: 2009-06-12
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Publication No.: US08507539B2Publication Date: 2013-08-13
- Inventor: Andrew John Harvey , Bernard Luke Flynn , Jorgen Alvar Mould , Dharam Paul , Gurmit Singh Gill , Justin Anthony Ripper , Rachel Christine Cooke , Julia Stephanie Crossman , Jonathan Bayldon Baell , Nathan Wayne Kuchel , Rajinder Singh
- Applicant: Andrew John Harvey , Bernard Luke Flynn , Jorgen Alvar Mould , Dharam Paul , Gurmit Singh Gill , Justin Anthony Ripper , Rachel Christine Cooke , Julia Stephanie Crossman , Jonathan Bayldon Baell , Nathan Wayne Kuchel , Rajinder Singh
- Applicant Address: AU Thebarton, South Austrialia
- Assignee: Bionomics Limited
- Current Assignee: Bionomics Limited
- Current Assignee Address: AU Thebarton, South Austrialia
- Agency: Knobbe, Martens, Olson & Bear, LLP
- International Application: PCT/AU2009/000739 WO 20090612
- International Announcement: WO2009/149508 WO 20091217
- Main IPC: A61K31/423
- IPC: A61K31/423 ; C07D263/54

Abstract:
The present invention relates to compounds useful in the modulation of potassium channel activity in cells, in particular the activity of Kv1.3 channels found in T cells. The invention also relates to the use of these compounds in the treatment or prevention of autoimmune and inflammatory diseases, including multiple sclerosis, pharmaceutical compositions containing these compounds and methods for their preparation.
Public/Granted literature
- US20110166130A1 NOVEL POTASSIUM CHANNEL BLOCKERS AND USES THEREOF Public/Granted day:2011-07-07
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