Systems and methods for the prevention or dissolution of hydrates in an undersea well. One example system includes a submersible isolation bell for capturing effluent being exhausted from the well, and an umbilical. A power cable supplies electric power to the submersible isolation bell, for example for heating of the interior of the submersible isolation bell to prevent or discourage the formation of methane hydrates and the precipitation of other byproducts. Diluents may be supplied to the submersible isolation bell to further discourage the formation of hydrates and precipitation of other byproducts. The diluents may be heated locally at the submersible isolation bell, using electric power supplied by the power cable. A conformable seal may substantially seal the submersible isolation bell to a riser or other structure at the wellhead.