A rescue appliance for evacuating physically-compromised persons is disclosed. A rescue appliance includes a platform configured to support a prone evacuee, a set of wheels coupled with the platform to support the platform relative to a floor surface, and a protection assembly coupled with the platform. The protection assembly is configurable to surround the prone evacuee to protect the evacuee from a fire. The protection assembly can be configured to encase the prone evacuee. The rescue appliance can be configured to be sufficiently buoyant to support an evacuee on water to allow evacuation in a flooding emergency. Two or more rescue appliances can be coupled together to form a train so that multiple persons can be evacuated simultaneously.