A set screw for use in association with spinal implant assemblies. The set screw includes a threaded base portion extending along a longitudinal axis and formed of a first material, and a friction member extending from a distal end of the threaded base portion and formed of a second material different from the first material. In one embodiment, the spinal implant assembly includes a connector member having a passage and an opening in communication with the passage, and an elongate support member positioned within the passage of the connector member. The set screw is threadedly engaged to the connector member and at least partially positioned within the opening, with a distal end portion of the friction member extending into the passage and compressed against an outer surface of the elongate support member to inhibit movement of the elongate support member within the passage.