Invention Grant
US08523937B2 Controlled drug delivery using a zein layer modified with levulinic acid
有权
使用用乙酰丙酸修饰的玉米醇溶蛋白层进行控制药物递送
- Patent Title: Controlled drug delivery using a zein layer modified with levulinic acid
- Patent Title (中): 使用用乙酰丙酸修饰的玉米醇溶蛋白层进行控制药物递送
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Application No.: US12273926Application Date: 2008-11-19
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Publication No.: US08523937B2Publication Date: 2013-09-03
- Inventor: Ashley P. Lindsay , Waleska Perez-Segarra , Patrick H. Ruane , Christine Casterline
- Applicant: Ashley P. Lindsay , Waleska Perez-Segarra , Patrick H. Ruane , Christine Casterline
- Applicant Address: US IN Bloomington
- Assignee: Cook Medical Technologies LLC
- Current Assignee: Cook Medical Technologies LLC
- Current Assignee Address: US IN Bloomington
- Agency: Brinks Hofer Gilson & Lione
- Main IPC: A61F2/06
- IPC: A61F2/06
Abstract:
The disclosure relates to medical devices coated with zein admixed with levulinic acid. The medical device may further include a therapeutic agent in contact with zein admixed with levulinic acid. Zein admixed with levulinic acid allows the therapeutic agent to be retained on the device during delivery and also controls the elution rate of the therapeutic agent following implantation. The disclosure further relates to methods of delivering a therapeutic agent on said medical devices as well as their use especially in the form of stents for prevention of restenosis.
Public/Granted literature
- US20090258050A1 Controlled Drug Delivery Using a Zein Layer Modified with Levulinic Acid Public/Granted day:2009-10-15
Information query
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