Invention Grant
- Patent Title: Methods and compositions for gene inactivation
- Patent Title (中): 用于基因失活的方法和组合物
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Application No.: US13068230Application Date: 2011-05-05
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Publication No.: US08524221B2Publication Date: 2013-09-03
- Inventor: Dale Ando , Michael C. Holmes , Yann Jouvenot , Gary Ka Leong Lee
- Applicant: Dale Ando , Michael C. Holmes , Yann Jouvenot , Gary Ka Leong Lee
- Applicant Address: US CA Richmond
- Assignee: Sangamo BioSciences, Inc.
- Current Assignee: Sangamo BioSciences, Inc.
- Current Assignee Address: US CA Richmond
- Agency: Pasternak Patent Law
- Agent Dahna S. Pasternak
- Main IPC: A01N63/00
- IPC: A01N63/00 ; C12P21/06
Abstract:
Disclosed herein are methods and compositions for inactivating CCR-5 genes, using zinc finger nucleases (ZFNs) comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding ZFNs, vectors comprising polynucleotides encoding ZFNs, such as adenovirus (Ad) vectors, and cells comprising polynucleotides encoding ZFNs and/or cells comprising ZFNs are also provided.
Public/Granted literature
- US20120308528A1 Methods and Compositions for Gene Inactivation Public/Granted day:2012-12-06
Information query
