Invention Grant
US08524225B2 Use of proline specific endoproteases to hydrolyse peptides and proteins
有权
使用脯氨酸特异性内切蛋白酶水解肽和蛋白质
- Patent Title: Use of proline specific endoproteases to hydrolyse peptides and proteins
- Patent Title (中): 使用脯氨酸特异性内切蛋白酶水解肽和蛋白质
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Application No.: US10572811Application Date: 2004-09-23
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Publication No.: US08524225B2Publication Date: 2013-09-03
- Inventor: Luppo Edens , Melissa Harvey , Robertus Antonius Mijndert Van Der Hoeven , Andre Leonardus De Roos
- Applicant: Luppo Edens , Melissa Harvey , Robertus Antonius Mijndert Van Der Hoeven , Andre Leonardus De Roos
- Applicant Address: NL Te Heerlen
- Assignee: DSM IP Assets B.V.
- Current Assignee: DSM IP Assets B.V.
- Current Assignee Address: NL Te Heerlen
- Agency: Nixon & Vanderhye
- Priority: EP03078012 20030923; EP03078496 20031106
- International Application: PCT/EP2004/010782 WO 20040923
- International Announcement: WO2005/027953 WO 20050331
- Main IPC: A61K38/48
- IPC: A61K38/48
Abstract:
The present invention relates to a process for the proteolytic hydrolysis of a peptide or a polypeptide, said peptide or polypeptide comprising 4 to 40, preferably 5 to 35, amino acid residues and said peptide or polypeptide is not hydrolysable by subtilisin whereby said peptide or polypeptide is hydrolysed by a proline specific endo protease at a pH of 6.5 or lower, preferably 5.5 or lower and more preferably 5.0 or lower to hydrolyse said peptide or polypeptide.
Public/Granted literature
- US20070031399A1 Use of proline specific endoproteases to hydrolyse peptides and proteins Public/Granted day:2007-02-08
Information query
IPC分类:
