Invention Grant
US08524483B2 Gene involved in quorum-sensing system of acetic acid bacterium, acetic acid bacterium bred by modification of the gene and method for production of vinegar by using the acetic acid bacterium 有权
基因参与乙酸细菌的群体感应系统,通过改变基因繁殖的乙酸细菌和使用乙酸菌生产醋的方法

  • Patent Title: Gene involved in quorum-sensing system of acetic acid bacterium, acetic acid bacterium bred by modification of the gene and method for production of vinegar by using the acetic acid bacterium
  • Patent Title (中): 基因参与乙酸细菌的群体感应系统,通过改变基因繁殖的乙酸细菌和使用乙酸菌生产醋的方法
  • Application No.: US12528066
    Application Date: 2008-01-18
  • Publication No.: US08524483B2
    Publication Date: 2013-09-03
  • Inventor: Aya Iida
  • Applicant: Aya Iida
  • Applicant Address: JP Aichi
  • Assignee: Mizkan Group Corporation
  • Current Assignee: Mizkan Group Corporation
  • Current Assignee Address: JP Aichi
  • Agency: Chalker Flores, LLP
  • Agent Chainey P. Singleton; Edwin S. Flores
  • Priority: JP2007-043635 20070223
  • International Application: PCT/JP2008/000049 WO 20080118
  • International Announcement: WO2008/102519 WO 20080828
  • Main IPC: C12N1/12
  • IPC: C12N1/12 C12N15/00 C12N9/00 C12N9/10 C12Q1/68 C07H21/04
Gene involved in quorum-sensing system of acetic acid bacterium, acetic acid bacterium bred by modification of the gene and method for production of vinegar by using the acetic acid bacterium
Abstract:
The object of the present invention is to provide a method for efficiently producing vinegar that contains a higher concentration of acetic acid, wherein a gene involved in the acetic acid fermentation ability is obtained, the acetic acid fermentation ability of an acetic acid bacterium is improved by reducing or deleting the function of the protein encoded by the gene. An acetic acid bacterium with a remarkably improved acetic acid fermentation ability was obtained by obtaining genes encoding an acyl homoserine lactone synthase and an acyl homoserine lactone receptor-type transcription factor that are involved in the quorum-sensing system in the acetic acid bacterium, and modifying the genes so as to reduce or delete the function of the quorum-sensing system. Further provided is a method for more efficiently producing vinegar containing a higher concentration of acetic acid by using the acetic acid bacterium.
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