Invention Grant
- Patent Title: Peptidomimetic macrocycles
- Patent Title (中): 拟肽大环
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Application No.: US12564910Application Date: 2009-09-22
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Publication No.: US08524653B2Publication Date: 2013-09-03
- Inventor: Huw M. Nash , David Allen Annis , Rosana Kapeller-Llbermann , Tomi K. Sawyer , Noriyuki Kawahata
- Applicant: Huw M. Nash , David Allen Annis , Rosana Kapeller-Llbermann , Tomi K. Sawyer , Noriyuki Kawahata
- Applicant Address: US MA Cambridge
- Assignee: Aileron Therapeutics, Inc.
- Current Assignee: Aileron Therapeutics, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61K38/02
- IPC: A61K38/02 ; C07K2/00
Abstract:
Biologically active crosslinked polypeptides with improved properties relative to their corresponding precursor polypeptides, having good cell penetration properties and reduced binding to human proteins, and methods of identifying and making such improved polypeptides are described.
Public/Granted literature
- US20100216688A1 PEPTIDOMIMETIC MACROCYCLES Public/Granted day:2010-08-26
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