Invention Grant
- Patent Title: MUC-1 cytoplasmic domain peptides as inhibitors of cancer
- Patent Title (中): MUC-1细胞质结构域肽作为癌症的抑制剂
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Application No.: US12580865Application Date: 2009-10-16
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Publication No.: US08524669B2Publication Date: 2013-09-03
- Inventor: Donald W. Kufe , Surender Kharbanda
- Applicant: Donald W. Kufe , Surender Kharbanda
- Applicant Address: US MA Boston US IL Vernon Hills
- Assignee: Dana-Farber Cancer Institute, Inc.,Genus Oncology, LLC
- Current Assignee: Dana-Farber Cancer Institute, Inc.,Genus Oncology, LLC
- Current Assignee Address: US MA Boston US IL Vernon Hills
- Agency: Parker Highlander PLLC
- Main IPC: A61P35/00
- IPC: A61P35/00
Abstract:
The invention provides for peptides from the Mucin 1 (MUC1) cytoplasmic domain and methods of use therefor. These peptides can inhibit MUC1 oligomerization, thereby preventing tumor cell growth, inducing tumor cell apoptosis and necrosis of tumor tissue in vivo.
Public/Granted literature
- US20100125055A1 MUC-1 CYTOPLASMIC DOMAIN PEPTIDES AS INHIBITORS OF CANCER Public/Granted day:2010-05-20
Information query
IPC分类:
| A | 人类生活必需 |
| A61 | 医学或兽医学；卫生学 |
| A61P | 化合物或药物制剂的特定治疗活性 |
| A61P35/00 | 抗肿瘤药 |
