Invention Grant
- Patent Title: Engineered CXCL12 alpha locked dimer polypeptide
- Patent Title (中): 工程化的CXCL12 alpha锁定二聚体多肽
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Application No.: US12956514Application Date: 2010-11-30
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Publication No.: US08524670B2Publication Date: 2013-09-03
- Inventor: Brian F. Volkman , Christopher T. Veldkamp , Francis C. Peterson , Thomas Sakmar , Christoph H. Seibert
- Applicant: Brian F. Volkman , Christopher T. Veldkamp , Francis C. Peterson , Thomas Sakmar , Christoph H. Seibert
- Applicant Address: US WI Milwaukee US NY New York
- Assignee: Medical College of Wisconsin Research Foundation,The Rockefeller University
- Current Assignee: Medical College of Wisconsin Research Foundation,The Rockefeller University
- Current Assignee Address: US WI Milwaukee US NY New York
- Agency: Quarles & Brady LLP
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
The present invention provides a novel CXCL12-α2 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, autoimmune disease, and HIV/AIDS.
Public/Granted literature
- US20110091410A1 Engineered CXCL12 Alpha Locked Dimer Polypeptide Public/Granted day:2011-04-21
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