Invention Grant
US08524699B2 Substituted dihydropyrazolones and use thereof as HIF-prolyl-4-hydroxylase inhibitors
有权
取代的二氢吡唑酮及其作为HIF-脯氨酰基-4-羟化酶抑制剂的用途
- Patent Title: Substituted dihydropyrazolones and use thereof as HIF-prolyl-4-hydroxylase inhibitors
- Patent Title (中): 取代的二氢吡唑酮及其作为HIF-脯氨酰基-4-羟化酶抑制剂的用途
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Application No.: US12447201Application Date: 2007-10-26
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Publication No.: US08524699B2Publication Date: 2013-09-03
- Inventor: Kai Thede , Ingo Flamme , Felix Oehme , Jens-Kerim Ergüden , Friederike Stoll , Joachim Schuhmacher , Hanno Wild , Peter Kolkhof , Hartmut Beck , Metin Akbaba , Mario Jeske
- Applicant: Kai Thede , Ingo Flamme , Felix Oehme , Jens-Kerim Ergüden , Friederike Stoll , Joachim Schuhmacher , Hanno Wild , Peter Kolkhof , Hartmut Beck , Metin Akbaba , Mario Jeske
- Applicant Address: DE Monheim
- Assignee: Bayer Intellectual Property GmbH
- Current Assignee: Bayer Intellectual Property GmbH
- Current Assignee Address: DE Monheim
- Agent Karen B. King
- Priority: DE102006050513 20061026
- International Application: PCT/EP2007/008977 WO 20071026
- International Announcement: WO2008/049538 WO 20080502
- Main IPC: A61K31/397
- IPC: A61K31/397 ; A61K31/5377 ; A61K31/501 ; A61K31/4965 ; A61K31/4725 ; A61K31/4427 ; A61K31/55 ; C07D413/14 ; C07D487/12 ; C07D403/14 ; C07D401/14 ; C07D417/14
Abstract:
The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing.
Public/Granted literature
- US20120264704A1 SUBSTITUTED DIHYDROPYRAZOLONES AND USE THEREOF AS HIF-PROLYL-4 -HYDROXYLASE INHIBITORS Public/Granted day:2012-10-18
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