Invention Grant
- Patent Title: Substituted benzoazepines as toll-like receptor modulators
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Application No.: US12859182Application Date: 2010-08-18
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Publication No.: US08524702B2Publication Date: 2013-09-03
- Inventor: James Jeffry Howbert , Gregory Dietsch , Robert Hershberg , Laurence E. Burgess , George A. Doherty , C. Todd Eary , Robert D. Groneberg , Zachary Jones
- Applicant: James Jeffry Howbert , Gregory Dietsch , Robert Hershberg , Laurence E. Burgess , George A. Doherty , C. Todd Eary , Robert D. Groneberg , Zachary Jones
- Applicant Address: US WA Seattle US CO Boulder
- Assignee: VentiRx Pharmaceuticals, Inc.,Array BioPharma, Inc.
- Current Assignee: VentiRx Pharmaceuticals, Inc.,Array BioPharma, Inc.
- Current Assignee Address: US WA Seattle US CO Boulder
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Heidi A. Erlacher; Lian Ouyang
- Main IPC: A61P35/00
- IPC: A61P35/00 ; A61K31/55 ; C07D223/16
Abstract:
Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease.
Public/Granted literature
- US20110118235A1 SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS Public/Granted day:2011-05-19
Information query
IPC分类:
| A | 人类生活必需 |
| A61 | 医学或兽医学；卫生学 |
| A61P | 化合物或药物制剂的特定治疗活性 |
| A61P35/00 | 抗肿瘤药 |
