Invention Grant
US08524705B2 2-oxo-2-(2-phenyl-5,6,7,8-tetrahydro-indolizin-3-yl)-acetamide derivatives and related compounds as antifungal agents
有权
2-氧代-2-（2-苯基-5,6,7,8-四氢 - 中氮茚-3-基） - 乙酰胺衍生物和相关化合物作为抗真菌剂
- Patent Title: 2-oxo-2-(2-phenyl-5,6,7,8-tetrahydro-indolizin-3-yl)-acetamide derivatives and related compounds as antifungal agents
- Patent Title (中): 2-氧代-2-（2-苯基-5,6,7,8-四氢 - 中氮茚-3-基） - 乙酰胺衍生物和相关化合物作为抗真菌剂
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Application No.: US12601284Application Date: 2008-05-21
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Publication No.: US08524705B2Publication Date: 2013-09-03
- Inventor: Lloyd James Payne , Robert Downham , Graham Edward Morris Sibley , Philip Edwards , Gareth Morse Davies
- Applicant: Lloyd James Payne , Robert Downham , Graham Edward Morris Sibley , Philip Edwards , Gareth Morse Davies
- Applicant Address: GB Greater Manchester
- Assignee: F2G Limited British Body Corporate
- Current Assignee: F2G Limited British Body Corporate
- Current Assignee Address: GB Greater Manchester
- Agency: Fulbright & Jaworski L.L.P.
- Priority: GB0710121.5 20070525
- International Application: PCT/GB2008/001738 WO 20080521
- International Announcement: WO2008/145963 WO 20081204
- Main IPC: A61K31/437
- IPC: A61K31/437 ; A61K31/496 ; A61K31/551 ; A61K31/5377 ; A01N43/90
Abstract:
The invention provides compounds of formula (I), and pharmaceutically and agriculturally acceptable salts thereof: wherein: R1, R2, R3, R4, R5, R6, R7, R8, A1, L1 and n are as defined herein. These compounds and their pharmaceutically acceptable salts are useful in the manufacture of medicaments for use in the prevention or treatment of a fungal disease. Compounds of formula (I), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.
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