Invention Grant
- Patent Title: Macrocyclic indoles as hepatitis C virus inhibitors
- Patent Title (中): 大环吲哚作为丙型肝炎病毒抑制剂
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Application No.: US12809160Application Date: 2008-12-23
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Publication No.: US08524716B2Publication Date: 2013-09-03
- Inventor: Pierre Jean-Marie Bernard Raboisson , Lili Hu , Sandrine Marie Helene Vendeville , Origène Nyanguile , Abdellah Tahri
- Applicant: Pierre Jean-Marie Bernard Raboisson , Lili Hu , Sandrine Marie Helene Vendeville , Origène Nyanguile , Abdellah Tahri
- Applicant Address: IE Little Island, Co Cork
- Assignee: Janssen R&D Ireland
- Current Assignee: Janssen R&D Ireland
- Current Assignee Address: IE Little Island, Co Cork
- Agent Andrea Jo Kamage
- Priority: EP07150415 20071224
- International Application: PCT/EP2008/068280 WO 20081223
- International Announcement: WO2009/080836 WO 20090702
- Main IPC: A61K31/496
- IPC: A61K31/496 ; C07D403/14
Abstract:
The present invention relates to inhibitors of HCV replication of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, wherein R1; R3; and R4 have the meaning defined in the claims. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in HCV therapy.
Public/Granted literature
- US20100273792A1 MACROCYCLIC INDOLES AS HEPATITIS C VIRUS INHIBITORS Public/Granted day:2010-10-28
Information query
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