Invention Grant
US08524726B2 Amido derivatives and their use as positive allosteric modulators of metabotropic glutamate receptors
失效
酰胺衍生物及其作为代谢型谷氨酸受体的正变构调节剂的用途
- Patent Title: Amido derivatives and their use as positive allosteric modulators of metabotropic glutamate receptors
- Patent Title (中): 酰胺衍生物及其作为代谢型谷氨酸受体的正变构调节剂的用途
-
Application No.: US13747366Application Date: 2013-01-22
-
Publication No.: US08524726B2Publication Date: 2013-09-03
- Inventor: Christelle Bolea
- Applicant: Addex Pharma, SA
- Applicant Address: CH Geneva
- Assignee: Addex Pharma S.A.
- Current Assignee: Addex Pharma S.A.
- Current Assignee Address: CH Geneva
- Agency: Law Offices of Gerard Bilotto, P.C.
- Agent Gerard Bilotto
- Priority: GB0713686.4 20070713
- Main IPC: C07D213/81
- IPC: C07D213/81
Abstract:
The present invention relates to novel compounds of Formula (I), wherein X1, X2, X3, X4, Am and Bn are defined as in Formula (I); invention compounds are modulators of metabotropic glutamate receptors—subtype 4 (“mGluR4”) which are useful for the treatment or prevention of central nervous system disorders as well as other disorders modulated by mGluR4 receptors. The invention is also directed to pharmaceutical compositions and the use of such compounds in the manufacture of medicaments, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR4 is involved.
Public/Granted literature
Information query
IPC分类:
