Invention Grant
US08524731B2 Use of opioid antagonists to attenuate endothelial cell proliferation and migration
有权
使用阿片样物质拮抗剂减轻内皮细胞增殖和迁移
- Patent Title: Use of opioid antagonists to attenuate endothelial cell proliferation and migration
- Patent Title (中): 使用阿片样物质拮抗剂减轻内皮细胞增殖和迁移
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Application No.: US11379010Application Date: 2006-04-17
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Publication No.: US08524731B2Publication Date: 2013-09-03
- Inventor: Jonathan Moss , Mark Lingen , Patrick A. Singleton , Joe G. N. Garcia , Chun-Su Yuan
- Applicant: Jonathan Moss , Mark Lingen , Patrick A. Singleton , Joe G. N. Garcia , Chun-Su Yuan
- Applicant Address: US IL Chicago
- Assignee: The University of Chicago
- Current Assignee: The University of Chicago
- Current Assignee Address: US IL Chicago
- Agency: Michael Best & Friedrich LLP
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; C07D221/18
Abstract:
The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.
Public/Granted literature
- US20060258696A1 USE OF OPIOID ANTAGONISTS TO ATTENUATE ENDOTHELIAL CELL PROLIFERATION AND MIGRATION Public/Granted day:2006-11-16
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