Invention Grant
- Patent Title: Pharmaceutical compositions
- Patent Title (中): 药物组合物
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Application No.: US13000442Application Date: 2009-06-25
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Publication No.: US08524747B2Publication Date: 2013-09-03
- Inventor: Kazuo Umezawa , Yuichi Ishikawa , Shigeru Nishiyama , Miyuki Tachibana , Ayumi Kaneda
- Applicant: Kazuo Umezawa , Yuichi Ishikawa , Shigeru Nishiyama , Miyuki Tachibana , Ayumi Kaneda
- Applicant Address: JP Tokyo
- Assignee: Keio University
- Current Assignee: Keio University
- Current Assignee Address: JP Tokyo
- Agency: Clark & Elbing LLP
- Priority: JP2008-166290 20080625
- International Application: PCT/JP2009/061636 WO 20090625
- International Announcement: WO2009/157515 WO 20091230
- Main IPC: A61K31/44
- IPC: A61K31/44
Abstract:
The object of the present invention is to provide a pharmaceutical composition that inhibits expression of iNOS and COX-2 without inhibiting NF-κB. The pharmaceutical composition that inhibits expression of iNOS and COX-2 without inhibiting NF-κB contains DTCM glutarimide of the Formula (I) as an effective ingredient, thereby being able to inhibit nitric oxide (NO) production and prostaglandin production.
Public/Granted literature
- US20110213001A1 PHARMACEUTICAL COMPOSITIONS Public/Granted day:2011-09-01
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