Invention Grant
US08524754B2 Polymorphic, crystalline and mesophase forms of sodium 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio) acetate, and uses thereof
有权
2-（5-溴-4-（4-环丙基萘-1-基）-4H-1,2,4-三唑-3-基硫基）乙酸钠的多晶型，结晶和中间相形式及其用途
- Patent Title: Polymorphic, crystalline and mesophase forms of sodium 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio) acetate, and uses thereof
- Patent Title (中): 2-（5-溴-4-（4-环丙基萘-1-基）-4H-1,2,4-三唑-3-基硫基）乙酸钠的多晶型，结晶和中间相形式及其用途
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Application No.: US13375607Application Date: 2011-01-05
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Publication No.: US08524754B2Publication Date: 2013-09-03
- Inventor: Irina Zamansky , Jean-Luc Girardet , Gabriel Galvin
- Applicant: Irina Zamansky , Jean-Luc Girardet , Gabriel Galvin
- Applicant Address: US CA San Diego
- Assignee: Ardea Biosciences, Inc.
- Current Assignee: Ardea Biosciences, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Wilson, Sonsini, Goodrich & Rosati
- International Application: PCT/US2011/020233 WO 20110105
- International Announcement: WO2011/085009 WO 20110714
- Main IPC: A61K31/41
- IPC: A61K31/41 ; A61K31/44 ; A61K31/56 ; C07D249/00
Abstract:
Crystalline polymorphs and solid mesophase forms of sodium 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetate are described. In addition, pharmaceutical compositions and uses of such compositions for the treatment of a variety of diseases and conditions are provided.
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