Invention Grant
- Patent Title: Modulators of ATP binding cassette transporters
- Patent Title (中): ATP结合盒转运蛋白的调节剂
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Application No.: US12704605Application Date: 2010-02-12
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Publication No.: US08524767B2Publication Date: 2013-09-03
- Inventor: Mark T. Miller , Sara S. Hadida Ruah , Brian R. Bear , Peter D. J. Grootenhuis , Jason McCartney
- Applicant: Mark T. Miller , Sara S. Hadida Ruah , Brian R. Bear , Peter D. J. Grootenhuis , Jason McCartney
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Micharl J. DiVerdi
- Main IPC: A61K31/36
- IPC: A61K31/36 ; C07D317/46
Abstract:
Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Public/Granted literature
- US20100249113A1 MODULATORS OF ATP BINDING CASSETTE TRANSPORTERS Public/Granted day:2010-09-30
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