Invention Grant
US08524772B2 Controlled release of N-acetylcysteine (NAC) for reduction of systemic and/or vascular inflammation
有权
用于减少全身和/或血管炎症的N-乙酰半胱氨酸（NAC）的控制释放
- Patent Title: Controlled release of N-acetylcysteine (NAC) for reduction of systemic and/or vascular inflammation
- Patent Title (中): 用于减少全身和/或血管炎症的N-乙酰半胱氨酸（NAC）的控制释放
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Application No.: US12595027Application Date: 2009-05-11
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Publication No.: US08524772B2Publication Date: 2013-09-03
- Inventor: Yadon Arad , Liang C. Dong
- Applicant: Yadon Arad , Liang C. Dong
- Applicant Address: US CA Los Altos
- Assignee: Tiara Pharmaceuticals, Inc.
- Current Assignee: Tiara Pharmaceuticals, Inc.
- Current Assignee Address: US CA Los Altos
- Agency: Cooley LLP
- International Application: PCT/US2009/043435 WO 20090511
- International Announcement: WO2009/137827 WO 20091112
- Main IPC: A61K31/225
- IPC: A61K31/225
Abstract:
The present invention provides a controlled-release composition which provides a therapeutically effective plasma concentration of N-acetylcysteine over prolonged period of time. The present invention also includes the use of the controlled-release composition, either alone or in combination with at least one additional active agent, for reduction of vascular inflammation marker and treatment of diseases, conditions, and/or symptoms associated with systemic and/or vascular inflammation in a patient. Furthermore, the present invention provides a process of making granules comprising N-acetylcysteine, or a salt, solvate, prodrug, and/or analog thereof.
Public/Granted literature
- US20110244045A1 CONTROLLED RELEASE OF N-ACETYLCYSTEINE (NAC) FOR REDUCTION OF SYSTEMIC AND/OR VASCULAR INFLAMMATION Public/Granted day:2011-10-06
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