Invention Grant
- Patent Title: Peptides with capacity to bind to scurfin and applications
- Patent Title (中): 能够结合scurfin和应用的肽
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Application No.: US12743616Application Date: 2008-11-14
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Publication No.: US08524860B2Publication Date: 2013-09-03
- Inventor: Inés Noelia Casares Lagar , Francisco Borrás Cuesta , Pablo Sarobe Ugarriza , Jesús Maria Prieto Valtueña , Juan José Lasarte Sagastibelza
- Applicant: Inés Noelia Casares Lagar , Francisco Borrás Cuesta , Pablo Sarobe Ugarriza , Jesús Maria Prieto Valtueña , Juan José Lasarte Sagastibelza
- Applicant Address: ES Navarra
- Assignee: Proyecto de Biomedicina CIMA, S.L.
- Current Assignee: Proyecto de Biomedicina CIMA, S.L.
- Current Assignee Address: ES Navarra
- Agency: Moore & Van Allen, PLLC
- Agent Tristan A. Fuierer; Andrew D. Gerschutz
- Priority: ES200703052 20071119
- International Application: PCT/ES2008/000716 WO 20081114
- International Announcement: WO2009/065982 WO 20090528
- Main IPC: C07K2/00
- IPC: C07K2/00
Abstract:
The invention relates to peptides of general formula (I), wherein X is absent or X is present and is X14 or X14-X15, wherein X14 and X15, independently from one another, represent an amino acid; their functional variants and fragments, and their pharmaceutically acceptable salts, having the capacity to bind to scurfin and inhibit its biological activity, therefore they regulate or block the activity of regulatory T (Treg) lymphocytes. They are applicable in the treatment of infectious and neoplastic diseases. (I) Arg-Asp-Phe-Gln-Ser-Phe-Arg-Lys-Met-Trp-Pro-Phe- Phe-X
Public/Granted literature
- US20100267623A1 PEPTIDES WITH CAPACITY TO BIND TO SCURFIN AND APPLICATIONS Public/Granted day:2010-10-21
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