Invention Grant
- Patent Title: Humanized antibodies against LIGHT and uses thereof
- Patent Title (中): 针对LIGHT的人源化抗体及其用途
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Application No.: US13256425Application Date: 2010-03-22
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Publication No.: US08524869B2Publication Date: 2013-09-03
- Inventor: Rodger Smith , Palanisamy Kanakaraj , Bridget A. Cooksey , Viktor Roschke , Craig Rosen
- Applicant: Rodger Smith , Palanisamy Kanakaraj , Bridget A. Cooksey , Viktor Roschke , Craig Rosen
- Applicant Address: US MD Rockville
- Assignee: Teva Biopharmaceuticals USA, Inc.
- Current Assignee: Teva Biopharmaceuticals USA, Inc.
- Current Assignee Address: US MD Rockville
- Agency: Foley & Lardner LLP
- International Application: PCT/US2010/028144 WO 20100322
- International Announcement: WO2010/111180 WO 20100930
- Main IPC: C07K16/00
- IPC: C07K16/00 ; A61K39/395 ; C07H21/04
Abstract:
The present invention is directed to antigen-binding polypeptides, or variants or derivatives thereof which specifically bind the LIGHT polypeptide. The invention is also directed to methods of making and using such antibodies specifically in the treatment or diagnosis of immune, inflammatory and malignant diseases or conditions (e.g. inflammatory bowel disease; Crohn's disease, ulcerative colitis, multiple sclerosis, rheumatoid arthritis and transplantation).
Public/Granted literature
- US20120100074A1 HUMANIZED ANTIBODIES AGAINST LIGHT AND USES THEREOF Public/Granted day:2012-04-26
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