Invention Grant
- Patent Title: Anti-platelet membrane glycoprotein VI monoclonal antibody
- Patent Title (中): 抗血小板膜糖蛋白VI单克隆抗体
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Application No.: US13721547Application Date: 2012-12-20
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Publication No.: US08524870B2Publication Date: 2013-09-03
- Inventor: Hiroshi Takayama , Kamon Shirakawa , Shoji Furusako , Yoshitaka Hosaka , Tomokazu Matsusue , Katsuki Naitoh , Yumi Hotta , Tetsushi Kawahara , Motoyasu Honda
- Applicant: Mochida Pharmaceutical Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Mochida Pharmaceutical Co., Ltd.
- Current Assignee: Mochida Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Foley & Lardner LLP
- Priority: JP2005-132665 20050428; JP2005-348534 20051201; WOPCT/JP2006/301818 20060127
- Main IPC: C12P21/08
- IPC: C12P21/08
Abstract:
The present invention provides an antibody which has the following features, its active fragment, or a derivative thereof: a) It specifically binds to human platelet membrane glycoprotein VI (GPVI); b) The function to activate a platelet and/or the function to induce a thrombocytopenia in vivo are low; and c) It at least partially depletes GPVI on the platelet membrane by contacting with a platelet.
Public/Granted literature
- US20130095120A1 ANTI-PLATELET MEMBRANE GLYCOPROTEIN VI MONOCLONAL ANTIBODY Public/Granted day:2013-04-18
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