Invention Grant
US08524875B2 Nucleic acids encoding SOX10 promoter and methods to isolate SOX10 expressing cells
有权
编码SOX10启动子的核酸和分离表达SOX10的细胞的方法
- Patent Title: Nucleic acids encoding SOX10 promoter and methods to isolate SOX10 expressing cells
- Patent Title (中): 编码SOX10启动子的核酸和分离表达SOX10的细胞的方法
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Application No.: US12645431Application Date: 2009-12-22
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Publication No.: US08524875B2Publication Date: 2013-09-03
- Inventor: Tatjana Sauka-Spengler , Sonja J. McKeown , Paola Betancur , Marianne Bronner
- Applicant: Tatjana Sauka-Spengler , Sonja J. McKeown , Paola Betancur , Marianne Bronner
- Applicant Address: US CA Pasadena
- Assignee: California Institute of Technology
- Current Assignee: California Institute of Technology
- Current Assignee Address: US CA Pasadena
- Agency: Christie, Parker & Hale, LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P21/06 ; C12N15/00 ; G01N33/53 ; C07H21/04
Abstract:
DNA enhancer sequences are provided for use in constructs to identify early stage embryonic cells. The enhancer sequences can be used in parallel with short-hairpin RNA in a vector construct for endogenously regulated gene knockdowns. The disclosed enhancer sequences can be used to isolate a selected population of early stage embryonic cells.
Public/Granted literature
- US20100311048A1 Neural Crest Enhancers and Methods for Use Public/Granted day:2010-12-09
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