Invention Grant
- Patent Title: Reduction of off-target RNA interference toxicity
- Patent Title (中): 减少脱靶RNA干扰毒性
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Application No.: US13552454Application Date: 2012-07-18
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Publication No.: US08524881B2Publication Date: 2013-09-03
- Inventor: Beverly L. Davidson , Alejandro Mas Monteys , Jodi L. McBride , Ryan Boudreau
- Applicant: Beverly L. Davidson , Alejandro Mas Monteys , Jodi L. McBride , Ryan Boudreau
- Applicant Address: US IA Iowa City
- Assignee: University of Iowa Research Foundation
- Current Assignee: University of Iowa Research Foundation
- Current Assignee Address: US IA Iowa City
- Agency: Viksnins Harris & Padys PLLP
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/02 ; A61K48/00
Abstract:
The present invention is directed to RNA interference (RNAi) molecules targeted against a nucleic acid sequence, and methods of using these RNAi molecules to reduce off-target toxicity.
Public/Granted literature
- US20120283424A1 REDUCTION OF OFF-TARGET RNA INTERFERENCE TOXICITY Public/Granted day:2012-11-08
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