Invention Grant
US08524905B2 Processes for preparing 6-(difluoromethoxy)[1]benzofuro[3,2-c]pyridine-9-carbaldehyde, a novel intermediate for the synthesis of PDE IV inhibitors
有权
制备6-（二氟甲氧基）[1]苯并呋喃并[3,2-c]吡啶-9-甲醛的方法，一种用于合成PDE IV抑制剂的新型中间体
![Processes for preparing 6-(difluoromethoxy)[1]benzofuro[3,2-c]pyridine-9-carbaldehyde, a novel intermediate for the synthesis of PDE IV inhibitors](/docs/US/2013-09-03/US08524905B2/abs.jpg.600x600.jpg)
- Patent Title: Processes for preparing 6-(difluoromethoxy)[1]benzofuro[3,2-c]pyridine-9-carbaldehyde, a novel intermediate for the synthesis of PDE IV inhibitors
- Patent Title (中): 制备6-（二氟甲氧基）[1]苯并呋喃并[3,2-c]吡啶-9-甲醛的方法，一种用于合成PDE IV抑制剂的新型中间体
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Application No.: US12601245Application Date: 2008-05-21
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Publication No.: US08524905B2Publication Date: 2013-09-03
- Inventor: Laxmikant Atmaram Gharat , Jitendra Maganbhai Gajera , Sandip Damodar Patil , Suresh M. Kadam
- Applicant: Laxmikant Atmaram Gharat , Jitendra Maganbhai Gajera , Sandip Damodar Patil , Suresh M. Kadam
- Applicant Address: CH La Chaux-de-Fonds
- Assignee: Glenmark Pharmaceuticals S.A.
- Current Assignee: Glenmark Pharmaceuticals S.A.
- Current Assignee Address: CH La Chaux-de-Fonds
- Agency: Blank Rome LLP
- Priority: IN955/MUM/2007 20070522
- International Application: PCT/IB2008/001272 WO 20080521
- International Announcement: WO2008/142542 WO 20081127
- Main IPC: C07D491/00
- IPC: C07D491/00
![Processes for preparing 6-(difluoromethoxy)[1]benzofuro[3,2-c]pyridine-9-carbaldehyde, a novel intermediate for the synthesis of PDE IV inhibitors](/abs-image/US/2013/09/03/US08524905B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to novel processes for preparing 6-(difluoromethoxy)[1]benzofuro[3,2-c]pyridine-9-carbaldehyde, which is a novel and useful intermediate for preparing compounds with PDE4 inhibitory activity, such as 3,5-dichloro-4-(6-difluoromethoxybenzo[4,5]furo[3,2-c]pyridin-9-ylcarboxamido)-1-pyridiniumolate.
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