Invention Grant
- Patent Title: Pyridyl derivatives as CFTR modulators
- Patent Title (中): 吡啶衍生物作为CFTR调节剂
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Application No.: US13533326Application Date: 2012-06-26
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Publication No.: US08524910B2Publication Date: 2013-09-03
- Inventor: Sara Hadida Ruah , Mark Miller , Jinglan Zhou , Brian Bear , Peter Grootenhuis
- Applicant: Sara Hadida Ruah , Mark Miller , Jinglan Zhou , Brian Bear , Peter Grootenhuis
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Michael J. DiVerdi
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D405/00
Abstract:
The present invention relates to modulators of Formula I and the accompanying definitions herein of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases such as cystic fibrosis using such modulators.
Public/Granted literature
- US20120270869A1 PYRIDYL DERIVATIVES AS CFTR MODULATORS Public/Granted day:2012-10-25
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