Invention Grant
- Patent Title: Acylsulfonamides and processes for producing the same
- Patent Title (中): 酰基磺酰胺及其制备方法
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Application No.: US12867812Application Date: 2009-02-23
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Publication No.: US08524947B2Publication Date: 2013-09-03
- Inventor: Hong-Gang Wang , Roman Manetsch , Xiangdong Hu , Sameer Kulkarni , Jiazhi Sun
- Applicant: Hong-Gang Wang , Roman Manetsch , Xiangdong Hu , Sameer Kulkarni , Jiazhi Sun
- Applicant Address: US FL Tampa US FL Tampa
- Assignee: University of South Florida,H. Lee Moffitt Cancer Center and Research Institute, Inc.
- Current Assignee: University of South Florida,H. Lee Moffitt Cancer Center and Research Institute, Inc.
- Current Assignee Address: US FL Tampa US FL Tampa
- Agency: Bryan Cave LLP
- International Application: PCT/US2009/034869 WO 20090223
- International Announcement: WO2009/105751 WO 20090827
- Main IPC: C07C321/00
- IPC: C07C321/00 ; C07D217/02 ; C07D211/06 ; C07D277/00
Abstract:
The present disclosure relates to acylsulfonamides and processes for their preparation. The processes involve a target-guided synthesis approach, whereby a thioacid and a sulfonyl azide are reacted in the presence of a biological target protein, a Bcl-2 family protein, to form the acylsulfonamide.
Public/Granted literature
- US20110130568A1 Acylsulfonamides and Processes for Producing the Same Public/Granted day:2011-06-02
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