A computer-implemented method of navigating a GUI can include, responsive to a user input initiating a navigation mode, overlaying, atop of the GUI located within a first layer, a virtual keyboard within a second layer, wherein the virtual keyboard includes a plurality of virtual keys. The method can include, for each virtual key, associating the virtual key with a region of the first layer including an area of the GUI beneath the virtual key. The method can include mapping each virtual key with a physical key of a physical keyboard communicatively linked with a computer rendering the GUI and, responsive to a user input selecting a physical key of the physical keyboard, selecting a region corresponding to the selected physical key. A level of magnification for the selected region can be increased within the first layer while keeping the virtual keyboard sizing constant.