Systems and methods may provide user control of a computer system via one or more sensors. Also, systems and methods may provide automated response of a computer system to information acquired via one or more sensors. The sensor(s) may be configured to measure distance, depth proximity and/or presence. In particular, the sensor(s) may be configured to measure a relative location, distance, presence, movements and/or gestures of one or more users of the computer system. Thus, the systems and methods may provide a computer user interface based on measurements of distance, depth, proximity, presence and/or movements by one or more sensors. For example, various contexts and/or operations of the computer system, at the operating system level and/or the application level, may be controlled, automatically and/or at a user's direction, based on information acquired by the sensor(s).