Various embodiments of systems and methods for dynamic binary translation in an interpreter are disclosed. An embodiment comprises a method for dynamic binary translation in an interpreter. One such method comprises: receiving non-native code comprising a sequence of one or more operators to be interpreted; building a static branch destination table associated with the operators, the static branch destination table specifying a static branch operator that branches to another operator in the sequence and a corresponding memory location to which the static branch operator branches; parsing the sequence of operators and building a cross-reference table that specifies a pointer to an operator function associated with the corresponding operator, an index of the operator in a native code sequence, and a call to a native operator; selecting a dynamic branch code template for the native operator; and based on the static branch table and the cross-reference table, emitting the native code sequence to be executed via a native processor.