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US08529767B2 Method for determining the percentage of recirculation in a fistula and/or cardiopulmonary recirculation relative to the total fistula recirculation and cardiopulmonary recirculation 有权
确定瘘管再循环的百分比和/或心肺再循环相对于总瘘再循环和心肺再循环的方法

  • Patent Title: Method for determining the percentage of recirculation in a fistula and/or cardiopulmonary recirculation relative to the total fistula recirculation and cardiopulmonary recirculation
  • Patent Title (中): 确定瘘管再循环的百分比和/或心肺再循环相对于总瘘再循环和心肺再循环的方法
  • Application No.: US12812261
    Application Date: 2009-01-08
  • Publication No.: US08529767B2
    Publication Date: 2013-09-10
  • Inventor: Wei Zhang
  • Applicant: Wei Zhang
  • Applicant Address: DE Bad Homburg
  • Assignee: Fresenius Medical Care Deutschland GmbH
  • Current Assignee: Fresenius Medical Care Deutschland GmbH
  • Current Assignee Address: DE Bad Homburg
  • Agency: Kenyon & Kenyon LLP
  • Priority: DE102008003714 20080109
  • International Application: PCT/EP2009/000054 WO 20090108
  • International Announcement: WO2009/087092 WO 20090716
  • Main IPC: B01D11/00
  • IPC: B01D11/00 ;  B01D61/00 ;  C02F1/44
Method for determining the percentage of recirculation in a fistula and/or cardiopulmonary recirculation relative to the total fistula recirculation and cardiopulmonary recirculation
Abstract:
The method according to the invention and the apparatus according to the invention are characterized in that the substitution rate QS is modified by a predefined amount upstream or downstream of the dialyzer or filter while the flow rate QFM of the liquid withdrawn through the dialyzer membrane is modified. The blood volume RBV(t) or a variable correlated with the blood volume, e.g. the hematocrit Hct(t), is determined before and after modifying the substitution rate or the flow rate of the liquid withdrawn through the dialyzer or filter membrane in order to calculate fistula recirculation RA. In addition, the total recirculation R is determined. The percentage of fistula recirculation (RA) and/or cardiopulmonary recirculation (RCP) relative to the total recirculation is calculated from the determined fistula recirculation (RA) and the sum R of fistula recirculation (RA) and cardiopulmonary recirculation (RCP).
Abstract(Chinese):

根据本发明的方法和根据本发明的装置的特征在于，通过透析器或过滤器的上游或下游的预定义量修改置换率QS，同时通过透析器膜抽出的液体的流量QFM被改变 。 血容量RBV（t）或与血容量相关的变量，例如 在改变通过透析器或滤膜抽出的液体的置换率或流速之前和之后确定血细胞比容Hct（t），以计算瘘再循环RA。 此外，确定总再循环R。 根据确定的瘘再循环（RA）和瘘管再循环（RA）和心肺再循环（RCP）的总和R计算出相对于总再循环的瘘再循环（RA）和/或心肺再循环（RCP）的百分比。

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