Invention Grant
- Patent Title: Methods and compositions related to the modulation of intercellular junctions
- Patent Title (中): 与细胞间连接调节相关的方法和组合
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Application No.: US11171490Application Date: 2005-06-29
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Publication No.: US08529889B2Publication Date: 2013-09-10
- Inventor: Aarthi Chandrasekaran , Shiladitya Sengupta , David A. Berry , Kristine Holley , Ganlin Zhao , Ram Sasisekharan
- Applicant: Aarthi Chandrasekaran , Shiladitya Sengupta , David A. Berry , Kristine Holley , Ganlin Zhao , Ram Sasisekharan
- Applicant Address: US MA Cambridge
- Assignee: Massachusetts Institute of Technology
- Current Assignee: Massachusetts Institute of Technology
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K38/47
- IPC: A61K38/47
Abstract:
The invention relates to compositions and methods for the modulation of the permeability of the epithelial cell barrier complex. In particular, the invention provides compositions and methods for using polysaccharides, preferably glycosaminoglycans, and agents that modify cell surface glycosaminoglycans, preferably glycosaminoglycan-degrading enzymes to modulate intercellular junctions. The compositions and methods provided can be used to facilitate the delivery of biologically active molecules.
Public/Granted literature
- US20060067927A1 Methods and compositions related to the modulation of intercellular junctions Public/Granted day:2006-03-30
Information query
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