Invention Grant
US08529893B2 Methods for treating IFN-γ mediated diseases using human anti-IFN-γ neutralizing antibodies as selective IFN-gamma pathway inhibitors
有权
使用人抗-γ-γ中和抗体作为选择性IFN-γ途径抑制剂治疗IFN-γ介导的疾病的方法
- Patent Title: Methods for treating IFN-γ mediated diseases using human anti-IFN-γ neutralizing antibodies as selective IFN-gamma pathway inhibitors
- Patent Title (中): 使用人抗-γ-γ中和抗体作为选择性IFN-γ途径抑制剂治疗IFN-γ介导的疾病的方法
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Application No.: US13476317Application Date: 2012-05-21
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Publication No.: US08529893B2Publication Date: 2013-09-10
- Inventor: Andrew A. Welcher , Hilary T. Chute , Yue-Sheng Li , Haichun Huang
- Applicant: Andrew A. Welcher , Hilary T. Chute , Yue-Sheng Li , Haichun Huang
- Applicant Address: US CA Thousand Oaks US NJ Princeton
- Assignee: Amgen Inc.,Medarex, Inc.
- Current Assignee: Amgen Inc.,Medarex, Inc.
- Current Assignee Address: US CA Thousand Oaks US NJ Princeton
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
This invention provides antibodies that interact with or bind to human interferon-gamma (IFN-γ) and methods for treating IFN-γ mediated diseases by administering a pharmaceutically effective amount of antibodies to IFN-γ. Methods of detecting the amount of IFN-γ in a sample using antibodies to IFN-γ are also provided.
Public/Granted literature
- US20120269819A1 Human Anti-IFN-gamma Neutralizing Antibodies as Selective IFN-gamma Pathway Inhibitors Public/Granted day:2012-10-25
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