Invention Grant
US08530178B2 Hydrolase detection system with caged substrates 失效
水解酶检测系统与笼式底物

  • Patent Title: Hydrolase detection system with caged substrates
  • Patent Title (中): 水解酶检测系统与笼式底物
  • Application No.: US12445378
    Application Date: 2007-10-17
  • Publication No.: US08530178B2
    Publication Date: 2013-09-10
  • Inventor: Daniel SobekJianghong Rao
  • Applicant: Daniel SobekJianghong Rao
  • Applicant Address: US CA Portola Valley
  • Assignee: Zymera, Inc.
  • Current Assignee: Zymera, Inc.
  • Current Assignee Address: US CA Portola Valley
  • Agency: Ishimaru & Associates LLP
  • International Application: PCT/US2007/081697 WO 20071017
  • International Announcement: WO2008/049036 WO 20080424
  • Main IPC: C12Q1/42
  • IPC: C12Q1/42
Hydrolase detection system with caged substrates
Abstract:
An enzyme detection method includes forming a caged substrate; releasing an uncaged substrate by cleaving a caging molecule from the caged substrate; and emitting a light emission from a Bioluminescence Resonance Energy Transfer luminescent nanocrystal conjugate reacting with the uncaged substrate.
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