Invention Grant
- Patent Title: Hydrolase detection system with caged substrates
- Patent Title (中): 水解酶检测系统与笼式底物
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Application No.: US12445378Application Date: 2007-10-17
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Publication No.: US08530178B2Publication Date: 2013-09-10
- Inventor: Daniel Sobek , Jianghong Rao
- Applicant: Daniel Sobek , Jianghong Rao
- Applicant Address: US CA Portola Valley
- Assignee: Zymera, Inc.
- Current Assignee: Zymera, Inc.
- Current Assignee Address: US CA Portola Valley
- Agency: Ishimaru & Associates LLP
- International Application: PCT/US2007/081697 WO 20071017
- International Announcement: WO2008/049036 WO 20080424
- Main IPC: C12Q1/42
- IPC: C12Q1/42

Abstract:
An enzyme detection method includes forming a caged substrate; releasing an uncaged substrate by cleaving a caging molecule from the caged substrate; and emitting a light emission from a Bioluminescence Resonance Energy Transfer luminescent nanocrystal conjugate reacting with the uncaged substrate.
Public/Granted literature
- US20100035290A1 ENZYME DETECTION SYSTEM WITH CAGED SUBSTRATES Public/Granted day:2010-02-11
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