Invention Grant
- Patent Title: Compositions and methods for using NADH oxidases
- Patent Title (中): 使用NADH氧化酶的组合物和方法
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Application No.: US12958949Application Date: 2010-12-02
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Publication No.: US08530213B2Publication Date: 2013-09-10
- Inventor: Andreas Bommarius , Bettina Bommarius , Jun-Ichiro Hirano , Vaijayanthi Thangavel , Jonathan Taejoo Park
- Applicant: Andreas Bommarius , Bettina Bommarius , Jun-Ichiro Hirano , Vaijayanthi Thangavel , Jonathan Taejoo Park
- Applicant Address: US GA Atlanta US GA Atlanta
- Assignee: Georgia Tech Research Corporation,Emory University
- Current Assignee: Georgia Tech Research Corporation,Emory University
- Current Assignee Address: US GA Atlanta US GA Atlanta
- Agency: Troutman Sanders LLP
- Agent Troy S. Kleckley; Ryan A. Schneider, Esq.
- Main IPC: C12N9/02
- IPC: C12N9/02 ; C12P41/00 ; C12P1/00 ; C12Q1/26

Abstract:
The present disclosure relates generally to bacterial NADH oxidases and, more particularly, to novel NADH oxidases obtained from Lactobacillus plantarum, and derivatives thereof that demonstrate enzymatic activity for NADH, NADPH, or both NADH and NADPH. The compositions comprising an NADH oxidase obtained from L. plantarum or derivatives thereof include: isolated enzymes; recombinantly produced enzymes and derivatives thereof, as well as catalytically active portions thereof; nucleic acids encoding an NADH oxidase obtained from L. plantarum, derivatives thereof, and portions thereof. The methods of the present invention include isolation of NADH oxidases obtained from L. plantarum, derivatives thereof, and portions thereof, and methods for enzymatic reactions comprising NADH oxidase obtained from L. plantarum, including the production of enantiomer-enriched organic compounds.
Public/Granted literature
- US20120003688A1 COMPOSITIONS AND METHODS FOR USING NADH OXIDASES Public/Granted day:2012-01-05
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