Invention Grant
- Patent Title: Therapeutic agents comprising pro-apoptotic proteins
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Application No.: US13281004Application Date: 2011-10-25
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Publication No.: US08530225B2Publication Date: 2013-09-10
- Inventor: Michael G. Rosenblum , Yuying Liu
- Applicant: Michael G. Rosenblum , Yuying Liu
- Applicant Address: US NV Carson City
- Assignee: Research Development Foundation
- Current Assignee: Research Development Foundation
- Current Assignee Address: US NV Carson City
- Agency: Parker Highlander PLLC
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C12N15/00 ; C07H21/02 ; C07K14/00
Abstract:
The present invention relates to targeted killing of a cell utilizing a chimeric polypeptide comprising a cell-specific targeting moiety and a signal transduction pathway factor. In a preferred embodiment, the signal transduction pathway factor is an apoptosis-inducing factor, such as granzyme B, granzyme A, or Bax.
Public/Granted literature
- US20120252097A1 Therapeutic Agents Comprising Pro-Apoptotic Proteins Public/Granted day:2012-10-04
Information query
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