Invention Grant
- Patent Title: Brain tumor targeting peptides and methods
- Patent Title (中): 脑肿瘤靶向肽和方法
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Application No.: US12950855Application Date: 2010-11-19
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Publication No.: US08530429B2Publication Date: 2013-09-10
- Inventor: Stephen Mark Robbins , Jennifer Rahn , Donna Lorraine Senger
- Applicant: Stephen Mark Robbins , Jennifer Rahn , Donna Lorraine Senger
- Applicant Address: CA Calgary
- Assignee: Arch Cancer Therapeutics, Inc.
- Current Assignee: Arch Cancer Therapeutics, Inc.
- Current Assignee Address: CA Calgary
- Agency: King & Spalding LLP
- Agent Peter J. Dehlinger
- Main IPC: A61P35/00
- IPC: A61P35/00 ; C07K7/00
Abstract:
A method of diagnosing and treating a human glioblastoma multiforme (GBM) brain tumor in a subject is disclosed. The method includes administering to the subject, an effective amount of composition having a peptide 12-20 amino acid residues in length and selected for its ability to bind preferentially to a subtype of human GBM cells identified as brain tumor initiating cells (BTICs) or highly invasive glioma cells (HIGCs). Also disclosed are a phage-display screening method for identifying such therapeutic peptides, and peptides that hind specifically to BTICs or HIGCs.
Public/Granted literature
- US20110129418A1 Brain Tumor Targeting Peptides and Methods Public/Granted day:2011-06-02
Information query
IPC分类:
| A | 人类生活必需 |
| A61 | 医学或兽医学；卫生学 |
| A61P | 化合物或药物制剂的特定治疗活性 |
| A61P35/00 | 抗肿瘤药 |
